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Safety and Tolerability of Antibody-Drug Conjugates in Cancer
Antibody-drug conjugates are monoclonal antibodies attached to biologically active drugs through chemical linkers that deliver and release cytotoxic agents at the tumor site, reducing the likelihood of systemic exposure and therefore toxicity. Currently, there are about 110 ongoing studies implement...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Springer International Publishing
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6399172/ https://www.ncbi.nlm.nih.gov/pubmed/30649747 http://dx.doi.org/10.1007/s40264-018-0775-7 |