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An Exome-Wide Sequencing Study of the GOLDN Cohort Reveals Novel Associations of Coding Variants and Fasting Plasma Lipids

Background: Associations of both common and rare genetic variants with fasting blood lipids have been extensively studied. However, most of the rare coding variants associated with lipids are population-specific, and exploration of genetic data from diverse population samples may enhance the identif...

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Detalles Bibliográficos
Autores principales: Geng, Xin, Irvin, Marguerite R., Hidalgo, Bertha, Aslibekyan, Stella, Srinivasasainagendra, Vinodh, An, Ping, Frazier-Wood, Alexis C., Tiwari, Hemant K., Dave, Tushar, Ryan, Kathleen, Ordovas, Jose M., Straka, Robert J., Feitosa, Mary F., Hopkins, Paul N., Borecki, Ingrid, Province, Michael A., Mitchell, Braxton D., Arnett, Donna K., Zhi, Degui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6399202/
https://www.ncbi.nlm.nih.gov/pubmed/30863429
http://dx.doi.org/10.3389/fgene.2019.00158