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Renal Damaging Effect Elicited by Bicalutamide Therapy Uncovered Multiple Action Mechanisms As Evidenced by the Cell Model

Bicalutamide (Bic) is frequently used in androgen deprivation therapy (ADT) for treating prostate cancer. ADT-induced hypogonadism was reported to have the potential to lead to acute kidney injury (AKI). ADT was also shown to induce bladder fibrosis via induction of the transforming growth factor (T...

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Detalles Bibliográficos
Autores principales: Peng, Chiung Chi, Chen, Chang-Yu, Chen, Chang-Rong, Chen, Chang-Jui, Shen, Kun-Hung, Chen, Kuan-Chou, Peng, Robert Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6399217/
https://www.ncbi.nlm.nih.gov/pubmed/30833616
http://dx.doi.org/10.1038/s41598-019-39533-3