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Renal Damaging Effect Elicited by Bicalutamide Therapy Uncovered Multiple Action Mechanisms As Evidenced by the Cell Model
Bicalutamide (Bic) is frequently used in androgen deprivation therapy (ADT) for treating prostate cancer. ADT-induced hypogonadism was reported to have the potential to lead to acute kidney injury (AKI). ADT was also shown to induce bladder fibrosis via induction of the transforming growth factor (T...
Autores principales: | Peng, Chiung Chi, Chen, Chang-Yu, Chen, Chang-Rong, Chen, Chang-Jui, Shen, Kun-Hung, Chen, Kuan-Chou, Peng, Robert Y. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6399217/ https://www.ncbi.nlm.nih.gov/pubmed/30833616 http://dx.doi.org/10.1038/s41598-019-39533-3 |
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