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NELFE-Dependent MYC Signature Identifies a Unique Cancer Subtype in Hepatocellular Carcinoma

The MYC oncogene is dysregulated in approximately 30% of liver cancer. In an effort to exploit MYC as a therapeutic target, including in hepatocellular carcinoma (HCC), strategies have been developed on the basis of MYC amplification or gene translocation. Due to the failure of these strategies to p...

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Detalles Bibliográficos
Autores principales: Dang, Hien, Pomyen, Yotsawat, Martin, Sean P., Dominguez, Dana A., Yim, Sun Young, Lee, Ju-Seog, Budhu, Anuradha, Shah, Ashesh P., Bodzin, Adam S., Wang, Xin Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6399236/
https://www.ncbi.nlm.nih.gov/pubmed/30833661
http://dx.doi.org/10.1038/s41598-019-39727-9