Cellular energy stress induces AMPK-mediated regulation of glioblastoma cell proliferation by PIKE-A phosphorylation

Phosphoinositide 3-kinase enhancer-activating Akt (PIKE-A), which associates with and potentiates Akt activity, is a pro-oncogenic factor that play vital role in cancer cell survival and growth. However, PIKE-A physiological functions under energy/nutrient deficiency are poorly understood. The AMP-a...

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Detalles Bibliográficos
Autores principales: Zhang, Shuai, Sheng, Hao, Zhang, Xiaoya, Qi, Qi, Chan, Chi Bun, Li, Leilei, Shan, Changliang, Ye, Keqiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6399291/
https://www.ncbi.nlm.nih.gov/pubmed/30833542
http://dx.doi.org/10.1038/s41419-019-1452-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6399291/
https://www.ncbi.nlm.nih.gov/pubmed/30833542
http://dx.doi.org/10.1038/s41419-019-1452-1

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