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SOX6 blocks the proliferation of BCR-ABL1(+) and JAK2V617F(+) leukemic cells

SOX6 is a HMG-box transcription factor expressed in a wide range of tissues. Recent data show that SOX6 expression is altered in different cancers, in the majority of cases being downregulated. To date, no data are available about SOX6 role in hematological malignancies. Here we demonstrate that SOX...

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Detalles Bibliográficos
Autores principales: Barbarani, Gloria, Fugazza, Cristina, Barabino, Silvia M. L., Ronchi, Antonella E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6399316/
https://www.ncbi.nlm.nih.gov/pubmed/30833651
http://dx.doi.org/10.1038/s41598-019-39926-4