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Variable outcomes of human heart attack recapitulated in genetically diverse mice

Clinical variation in patient responses to myocardial infarction (MI) has been difficult to model in laboratory animals. To assess the genetic basis of variation in outcomes after heart attack, we characterized responses to acute MI in the Collaborative Cross (CC), a multi-parental panel of genetica...

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Detalles Bibliográficos
Autores principales: Salimova, Ekaterina, Nowak, Kristen J., Estrada, Ana C., Furtado, Milena B., McNamara, Elyshia, Nguyen, Quang, Balmer, Lois, Preuss, Christoph, Holmes, Jeffrey W., Ramialison, Mirana, Morahan, Grant, Rosenthal, Nadia A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6399323/
https://www.ncbi.nlm.nih.gov/pubmed/30854227
http://dx.doi.org/10.1038/s41536-019-0067-6