Cargando…
Variable outcomes of human heart attack recapitulated in genetically diverse mice
Clinical variation in patient responses to myocardial infarction (MI) has been difficult to model in laboratory animals. To assess the genetic basis of variation in outcomes after heart attack, we characterized responses to acute MI in the Collaborative Cross (CC), a multi-parental panel of genetica...
Autores principales: | Salimova, Ekaterina, Nowak, Kristen J., Estrada, Ana C., Furtado, Milena B., McNamara, Elyshia, Nguyen, Quang, Balmer, Lois, Preuss, Christoph, Holmes, Jeffrey W., Ramialison, Mirana, Morahan, Grant, Rosenthal, Nadia A. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6399323/ https://www.ncbi.nlm.nih.gov/pubmed/30854227 http://dx.doi.org/10.1038/s41536-019-0067-6 |
Ejemplares similares
-
Combinatorial Ranking of Gene Sets to Predict Disease Relapse: The Retinoic Acid Pathway in Early Prostate Cancer
por: Nim, Hieu T., et al.
Publicado: (2017) -
Gene Expression Networks in the Murine Pulmonary Myocardium Provide Insight into the Pathobiology of Atrial Fibrillation
por: Boutilier, Jordan K., et al.
Publicado: (2017) -
Molecular Consequences of the Myopathy-Related D286G Mutation on Actin Function
por: Fan, Jun, et al.
Publicado: (2018) -
Rapid Identification of Major-Effect Genes Using the Collaborative Cross
por: Ram, Ramesh, et al.
Publicado: (2014) -
Nebulin nemaline myopathy recapitulated in a compound heterozygous mouse model with both a missense and a nonsense mutation in Neb
por: Laitila, Jenni M., et al.
Publicado: (2020)