Hedgehog signaling in the airway epithelium of patients with chronic obstructive pulmonary disease

Genome-wide association studies have linked gene variants of the receptor patched homolog 1 (PTCH1) with chronic obstructive pulmonary disease (COPD). However, its biological role in the disease is unclear. Our objective was to determine the expression pattern and biological role of PTCH1 in the lun...

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Detalles Bibliográficos
Autores principales: Tam, A., Hughes, M., McNagny, K. M., Obeidat, M., Hackett, T. L., Leung, J. M., Shaipanich, T., Dorscheid, D. R., Singhera, G. K., Yang, C. W. T., Paré, P. D., Hogg, J. C., Nickle, D., Sin, D. D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6399332/
https://www.ncbi.nlm.nih.gov/pubmed/30833624
http://dx.doi.org/10.1038/s41598-019-40045-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6399332/
https://www.ncbi.nlm.nih.gov/pubmed/30833624
http://dx.doi.org/10.1038/s41598-019-40045-3

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