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Cationic Intrinsically Disordered Antimicrobial Peptides (CIDAMPs) Represent a New Paradigm of Innate Defense with a Potential for Novel Anti-Infectives

In the search for potential mechanisms underlying the remarkable resistance of healthy skin against infection by soil bacteria like Pseudomonas (P.) aeruginosa we identified fragments of the intrinsically disordered protein hornerin as potent microbicidal agents in the stratum corneum. We found that...

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Detalles Bibliográficos
Autores principales: Latendorf, Ties, Gerstel, Ulrich, Wu, Zhihong, Bartels, Joachim, Becker, Alexander, Tholey, Andreas, Schröder, Jens-Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6399351/
https://www.ncbi.nlm.nih.gov/pubmed/30833614
http://dx.doi.org/10.1038/s41598-019-39219-w