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Light-Controlled Affinity Purification of Protein Complexes Exemplified by the Resting ZAP70 Interactome
Multiprotein complexes control the behavior of cells, such as of lymphocytes of the immune system. Methods to affinity purify protein complexes and to determine their interactome by mass spectrometry are thus widely used. One drawback of these methods is the presence of false positives. In fact, the...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6399385/ https://www.ncbi.nlm.nih.gov/pubmed/30863395 http://dx.doi.org/10.3389/fimmu.2019.00226 |