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Shorter TCR β-Chains Are Highly Enriched During Thymic Selection and Antigen-Driven Selection
The adaptive immune system uses several strategies to generate a repertoire of T cell receptors (TCR) with sufficient diversity to recognize the universe of potential pathogens. However, it remains unclear how differences in the T cell receptor (TCR) contribute to heterogeneity in T cell state. In t...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6399399/ https://www.ncbi.nlm.nih.gov/pubmed/30863407 http://dx.doi.org/10.3389/fimmu.2019.00299 |