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Antibody Specific B-Cell Epitope Predictions: Leveraging Information From Antibody-Antigen Protein Complexes

B-cells can neutralize pathogenic molecules by targeting them with extreme specificity using receptors secreted or expressed on their surface (antibodies). This is achieved via molecular interactions between the paratope (i.e., the antibody residues involved in the binding) and the interacting regio...

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Detalles Bibliográficos
Autores principales: Jespersen, Martin Closter, Mahajan, Swapnil, Peters, Bjoern, Nielsen, Morten, Marcatili, Paolo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6399414/
https://www.ncbi.nlm.nih.gov/pubmed/30863406
http://dx.doi.org/10.3389/fimmu.2019.00298