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Developmental Axon Degeneration Requires TRPV1-Dependent Ca(2+) Influx

Development of the nervous system relies on a balance between axon and dendrite growth and subsequent pruning and degeneration. The developmental degeneration of dorsal root ganglion (DRG) sensory axons has been well studied in part because it can be readily modeled by removing the trophic support b...

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Detalles Bibliográficos
Autores principales: Johnstone, Aaron D., de Léon, Andrés, Unsain, Nicolás, Gibon, Julien, Barker, Philip A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6399429/
https://www.ncbi.nlm.nih.gov/pubmed/30838324
http://dx.doi.org/10.1523/ENEURO.0019-19.2019