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Genetic control of the mouse HDL proteome defines HDL traits, function, and heterogeneity

HDLs are nanoparticles with more than 80 associated proteins, phospholipids, cholesterol, and cholesteryl esters. The potential inverse relation of HDL to coronary artery disease (CAD) and the effects of HDL on myriad other inflammatory conditions warrant a better understanding of the genetic basis...

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Detalles Bibliográficos
Autores principales: Pamir, Nathalie, Pan, Calvin, Plubell, Deanna L., Hutchins, Patrick M., Tang, Chongren, Wimberger, Jake, Irwin, Angela, Vallim, Thomas Q. de Aguiar, Heinecke, Jay W., Lusis, Aldons J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Biochemistry and Molecular Biology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6399512/
https://www.ncbi.nlm.nih.gov/pubmed/30622162
http://dx.doi.org/10.1194/jlr.M090555