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Precise Detection of Gene Mutations in Fine-Needle Aspiration Specimens of the Papillary Thyroid Microcarcinoma Using Next-Generation Sequencing

PURPOSE: To assess the feasibility of next-generation sequencing (NGS) to detect mutations in BRAF, RAS, TERT promoter, and TP53 genes in ultrasound-guided fine-needle aspiration (FNA) biopsy samples of the papillary thyroid microcarcinoma (PTMC). METHODS: A total of 135 FNA samples out of 135 patie...

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Detalles Bibliográficos
Autores principales: Yu, Feng-xia, Hu, Min-xia, Zhao, Han-xue, Niu, Li-juan, Rong, Xue-yu, Li, Wei-hua, Zhu, Qiang, Ying, Jian-ming, Lyu, Ning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6399538/
https://www.ncbi.nlm.nih.gov/pubmed/30915113
http://dx.doi.org/10.1155/2019/4723958