Less Vertebral Bone Mass after Treatment with Macitentan in Mice: A Pilot Study

PURPOSE: Blood vessels and skeleton interact together. Endothelin-1 is a potent vasoconstrictor and also has an effect on bone metabolism. The dual antagonist to both endothelin-1 type A and B receptors, Macitentan, has been approved for clinical management of pulmonary arterial hypertension while l...

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Detalles Bibliográficos
Autores principales: Liu, Zhong-Yu, Au, Man-Ting, He, Tian-Wei, Yang, Bu, Liu, Bin, Zhang, Liang-Ming, Luo, Chun-Xiao, Rong, Li-Min, Wen, Chun-Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6399551/
https://www.ncbi.nlm.nih.gov/pubmed/30911541
http://dx.doi.org/10.1155/2019/2075968

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6399551/
https://www.ncbi.nlm.nih.gov/pubmed/30911541
http://dx.doi.org/10.1155/2019/2075968

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