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Less Vertebral Bone Mass after Treatment with Macitentan in Mice: A Pilot Study
PURPOSE: Blood vessels and skeleton interact together. Endothelin-1 is a potent vasoconstrictor and also has an effect on bone metabolism. The dual antagonist to both endothelin-1 type A and B receptors, Macitentan, has been approved for clinical management of pulmonary arterial hypertension while l...
Autores principales: | Liu, Zhong-Yu, Au, Man-Ting, He, Tian-Wei, Yang, Bu, Liu, Bin, Zhang, Liang-Ming, Luo, Chun-Xiao, Rong, Li-Min, Wen, Chun-Yi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6399551/ https://www.ncbi.nlm.nih.gov/pubmed/30911541 http://dx.doi.org/10.1155/2019/2075968 |
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