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Evaluation of a Dual Isolation Width Acquisition Method for Isobaric Labeling Ratio Decompression

[Image: see text] Isobaric labeling is a highly precise approach for protein quantification. However, due to the isolation interference problem, isobaric tagging suffers from ratio underestimation at the MS2 level. The use of narrow isolation widths is a rational approach to alleviate the interferen...

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Detalles Bibliográficos
Autores principales: Roumeliotis, Theodoros I., Weisser, Hendrik, Choudhary, Jyoti S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2018
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6399672/
https://www.ncbi.nlm.nih.gov/pubmed/30576155
http://dx.doi.org/10.1021/acs.jproteome.8b00870