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Imidazole-modified G-quadruplex DNA as metal-triggered peroxidase

Four imidazoles, serving as metalloprotein-inspired ligands for complexing a range of transition metal cations, were incorporated into tetramolecular G-quadruplex DNA structures. Modified quadruplexes were found to complex Cu(ii), Ni(ii), Zn(ii) and Co(ii) in a 1 : 1 ratio with unprecedented strong...

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Detalles Bibliográficos
Autores principales: Punt, Philip M., Clever, Guido H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6399679/
https://www.ncbi.nlm.nih.gov/pubmed/30931097
http://dx.doi.org/10.1039/c8sc05020a