Towards embedding Caco-2 model of gut interface in a microfluidic device to enable multi-organ models for systems biology

BACKGROUND: A cancer cell line originating from human epithelial colorectal adenocarcinoma (Caco-2 cells) serves as a high capacity model for a preclinical screening of drugs. Recent need for incorporating barrier tissue into multi-organ chips calls for inclusion of Caco-2 cells into microperfused e...

Descripción completa

Detalles Bibliográficos
Autores principales: Sakharov, Dmitry, Maltseva, Diana, Knyazev, Evgeny, Nikulin, Sergey, Poloznikov, Andrey, Shilin, Sergey, Baranova, Ancha, Tsypina, Irina, Tonevitsky, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6399809/
https://www.ncbi.nlm.nih.gov/pubmed/30836980
http://dx.doi.org/10.1186/s12918-019-0686-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6399809/
https://www.ncbi.nlm.nih.gov/pubmed/30836980
http://dx.doi.org/10.1186/s12918-019-0686-y

Ejemplares similares