Cargando…
Semi-nonparametric modeling of topological domain formation from epigenetic data
BACKGROUND: Hi-C experiments capturing the 3D genome architecture have led to the discovery of topologically-associated domains (TADs) that form an important part of the 3D genome organization and appear to play a role in gene regulation and other functions. Several histone modifications have been i...
| Autores principales: | , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2019
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6399866/ https://www.ncbi.nlm.nih.gov/pubmed/30867673 http://dx.doi.org/10.1186/s13015-019-0142-y |