Detection of Alzheimer’s disease (AD) specific tau pathology with conformation-selective anti-tau monoclonal antibody in co-morbid frontotemporal lobar degeneration-tau (FTLD-tau)

Pathological tau aggregates in Alzheimer’s disease (AD) and frontotemporal lobar degeneration-tau (FTLD-tau) adopt distinct conformations differentiated by the AD-tau specific monoclonal antibody (mAb) GT-38 that are not readily visualized using phosphorylation-specific anti-tau mAbs. To determine t...

Descripción completa

Detalles Bibliográficos
Autores principales: Gibbons, Garrett S., Kim, Soo-Jung, Robinson, John L., Changolkar, Lakshmi, Irwin, David J., Shaw, Leslie M., Lee, Virginia M.-Y., Trojanowski, John Q.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6399892/
https://www.ncbi.nlm.nih.gov/pubmed/30832741
http://dx.doi.org/10.1186/s40478-019-0687-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6399892/
https://www.ncbi.nlm.nih.gov/pubmed/30832741
http://dx.doi.org/10.1186/s40478-019-0687-5

Ejemplares similares