The neoepitope landscape of breast cancer: implications for immunotherapy

BACKGROUND: Cancer immunotherapy with immune checkpoint blockade (CKB) is now standard of care for multiple cancers. The clinical response to CKB is associated with T cell immunity targeting cancer-induced mutations that generate novel HLA-binding epitopes (neoepitopes). METHODS: Here, we developed...

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Detalles Bibliográficos
Autores principales: Narang, Pooja, Chen, Meixuan, Sharma, Amit A., Anderson, Karen S., Wilson, Melissa A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6399957/
https://www.ncbi.nlm.nih.gov/pubmed/30832597
http://dx.doi.org/10.1186/s12885-019-5402-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6399957/
https://www.ncbi.nlm.nih.gov/pubmed/30832597
http://dx.doi.org/10.1186/s12885-019-5402-1

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