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The neoepitope landscape of breast cancer: implications for immunotherapy

BACKGROUND: Cancer immunotherapy with immune checkpoint blockade (CKB) is now standard of care for multiple cancers. The clinical response to CKB is associated with T cell immunity targeting cancer-induced mutations that generate novel HLA-binding epitopes (neoepitopes). METHODS: Here, we developed...

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Detalles Bibliográficos
Autores principales:	Narang, Pooja, Chen, Meixuan, Sharma, Amit A., Anderson, Karen S., Wilson, Melissa A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6399957/ https://www.ncbi.nlm.nih.gov/pubmed/30832597 http://dx.doi.org/10.1186/s12885-019-5402-1

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