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FAT4 regulates the EMT and autophagy in colorectal cancer cells in part via the PI3K-AKT signaling axis

BACKGROUND: FAT4 functions as a tumor suppressor, and previous findings have demonstrated that FAT4 can inhibit the epithelial-to-mesenchymal transition (EMT) and the proliferation of gastric cancer cells. However, few studies have investigated the role of FAT4 in the development of colorectal cance...

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Detalles Bibliográficos
Autores principales: Wei, Ran, Xiao, Yuhong, Song, Yi, Yuan, Huiping, Luo, Jun, Xu, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6399964/
https://www.ncbi.nlm.nih.gov/pubmed/30832706
http://dx.doi.org/10.1186/s13046-019-1043-0