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Cyclopamine Suppresses Human Esophageal Carcinoma Cell Growth by Inhibiting Glioma-Associated Oncogene Protein-1, a Marker of Human Esophageal Carcinoma Progression

BACKGROUND: Esophageal carcinoma is a common gastrointestinal tumor in humans. Cyclopamine, a Hedgehog (Hh)-pathway-specific inhibitor, is an effective chemotherapeutic drug for suppressing tumor cell differentiation, with unclear mechanisms. We investigated glioma-associated oncogene protein-1 (Gli...

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Detalles Bibliográficos
Autores principales: Yu, Jing, Wu, Ruinuan, Wang, Zhenyu, Chen, Shuxian, Chen, Suzuan, Guo, Guanghua, Liu, Zhaohui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6400020/
https://www.ncbi.nlm.nih.gov/pubmed/30807555
http://dx.doi.org/10.12659/MSM.912858