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Cyclopamine Suppresses Human Esophageal Carcinoma Cell Growth by Inhibiting Glioma-Associated Oncogene Protein-1, a Marker of Human Esophageal Carcinoma Progression

BACKGROUND: Esophageal carcinoma is a common gastrointestinal tumor in humans. Cyclopamine, a Hedgehog (Hh)-pathway-specific inhibitor, is an effective chemotherapeutic drug for suppressing tumor cell differentiation, with unclear mechanisms. We investigated glioma-associated oncogene protein-1 (Gli...

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Detalles Bibliográficos
Autores principales:	Yu, Jing, Wu, Ruinuan, Wang, Zhenyu, Chen, Shuxian, Chen, Suzuan, Guo, Guanghua, Liu, Zhaohui
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	International Scientific Literature, Inc. 2019
Materias:	Lab/In Vitro Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6400020/ https://www.ncbi.nlm.nih.gov/pubmed/30807555 http://dx.doi.org/10.12659/MSM.912858

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