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RNA-binding protein Ptbp1 is essential for BCR-mediated antibody production

The RNA-binding protein polypyrimidine tract-binding protein-1 (Ptbp1) binds to the pyrimidine-rich sequence of target RNA and controls gene expression via post-transcriptional regulation such as alternative splicing. Although Ptbp1 is highly expressed in B lymphocytes, its role to date is largely u...

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Detalles Bibliográficos
Autores principales: Sasanuma, Hiroki, Ozawa, Manabu, Yoshida, Nobuaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6400050/
https://www.ncbi.nlm.nih.gov/pubmed/30476084
http://dx.doi.org/10.1093/intimm/dxy077