The Antimicrobials Anacardic Acid and Curcumin Are Not-Competitive Inhibitors of Gram-Positive Bacterial Pathogenic Glyceraldehyde-3-Phosphate Dehydrogenase by a Mechanism Unrelated to Human C5a Anaphylatoxin Binding

The ubiquitous and highly abundant glycolytic enzyme D-glyceraldehyde-3-phosphate dehydrogenase (GAPDH) is pivotal for the energy and carbon metabolism of most organisms, including human pathogenic bacteria. For bacteria that depend mostly on glycolysis for survival, GAPDH is an attractive target fo...

Descripción completa

Detalles Bibliográficos
Autores principales: Gómez, Sara, Querol-García, Javier, Sánchez-Barrón, Gara, Subias, Marta, González-Alsina, Àlex, Franco-Hidalgo, Virginia, Albertí, Sebastián, Rodríguez de Córdoba, Santiago, Fernández, Francisco J., Vega, M. Cristina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6400076/
https://www.ncbi.nlm.nih.gov/pubmed/30863383
http://dx.doi.org/10.3389/fmicb.2019.00326

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6400076/
https://www.ncbi.nlm.nih.gov/pubmed/30863383
http://dx.doi.org/10.3389/fmicb.2019.00326

Ejemplares similares