Effects of Thioflavin T and GSK-3 Inhibition on Lifespan and Motility in a Caenorhabditis elegans Model of Tauopathy

The nematode Caenorhabditis elegans (C. elegans) is a powerful model organism to study lifespan and aging, protein aggregation, and neurodegeneration, as well as to carry out drug screenings. The C. elegans strain aex-3/T337 expresses human pathogenic V337M mutant tau under a pan-neuronal promoter a...

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Detalles Bibliográficos
Autores principales: Gamir-Morralla, Andrea, Sacristán, Sandra, Medina, Miguel, Iglesias, Teresa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2019
Materias:
Research Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6400111/
https://www.ncbi.nlm.nih.gov/pubmed/30842997
http://dx.doi.org/10.3233/ADR-180087

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6400111/
https://www.ncbi.nlm.nih.gov/pubmed/30842997
http://dx.doi.org/10.3233/ADR-180087

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