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Journey to the center of the protein: allostery from multitemperature multiconformer X-ray crystallography
Proteins inherently fluctuate between conformations to perform functions in the cell. For example, they sample product-binding, transition-state-stabilizing and product-release states during catalysis, and they integrate signals from remote regions of the structure for allosteric regulation. However...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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International Union of Crystallography
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6400254/ https://www.ncbi.nlm.nih.gov/pubmed/30821702 http://dx.doi.org/10.1107/S2059798318017941 |