A new highly sensitive real-time quantitative-PCR method for detection of BCR-ABL1 to monitor minimal residual disease in chronic myeloid leukemia after discontinuation of imatinib

Tyrosine kinase inhibitors (TKIs) targeting the BCR-ABL1 fusion protein, encoded by the Philadelphia chromosome, have drastically improved the outcomes for patients with chronic myeloid leukemia (CML). Although several real-time quantitative polymerase chain reaction (RQ-PCR) kits for the detection...

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Detalles Bibliográficos
Autores principales: Kitamura, Hiroaki, Tabe, Yoko, Ai, Tomohiko, Tsuchiya, Koji, Yuri, Maiko, Misawa, Shigeki, Horii, Takashi, Kawaguchi, Atsushi, Ohsaka, Akimichi, Kimura, Shinya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6400442/
https://www.ncbi.nlm.nih.gov/pubmed/30835732
http://dx.doi.org/10.1371/journal.pone.0207170

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6400442/
https://www.ncbi.nlm.nih.gov/pubmed/30835732
http://dx.doi.org/10.1371/journal.pone.0207170

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