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Novel alanine serine cysteine transporter 2 (ASCT2) inhibitors based on sulfonamide and sulfonic acid ester scaffolds

The neutral amino acid transporter alanine serine cysteine transporter 2 (ASCT2) belongs to the solute carrier 1 (SLC1) family of transport proteins and transports neutral amino acids, such as alanine and glutamine, into the cell in exchange with intracellular amino acids. This amino acid transport...

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Detalles Bibliográficos
Autores principales: Ndaru, Elias, Garibsingh, Rachel-Ann A., Shi, YueYue, Wallace, Evan, Zakrepine, Paul, Wang, Jiali, Schlessinger, Avner, Grewer, Christof
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6400523/
https://www.ncbi.nlm.nih.gov/pubmed/30718375
http://dx.doi.org/10.1085/jgp.201812276