The developmental stage of the hematopoietic niche regulates lineage in MLL-rearranged leukemia

Leukemia phenotypes vary with age of onset. Delineating mechanisms of age specificity in leukemia could improve disease models and uncover new therapeutic approaches. Here, we used heterochronic transplantation of leukemia driven by MLL/KMT2A translocations to investigate the contribution of the age...

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Detalles Bibliográficos
Autores principales: Rowe, R. Grant, Lummertz da Rocha, Edroaldo, Sousa, Patricia, Missios, Pavlos, Morse, Michael, Marion, William, Yermalovich, Alena, Barragan, Jessica, Mathieu, Ronald, Jha, Deepak Kumar, Fleming, Mark D., North, Trista E., Daley, George Q.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2019
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6400531/
https://www.ncbi.nlm.nih.gov/pubmed/30728174
http://dx.doi.org/10.1084/jem.20181765

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6400531/
https://www.ncbi.nlm.nih.gov/pubmed/30728174
http://dx.doi.org/10.1084/jem.20181765

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