FoxP3 and Ezh2 regulate Tfr cell suppressive function and transcriptional program

Follicular regulatory T (Tfr) cells are a regulatory T cell subset that controls antibody production by inhibiting T follicular helper (Tfh)–mediated help to B cells. Tfh and Tfr cells possess opposing functions suggesting unique programming. Here we elucidated the transcriptional program controllin...

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Detalles Bibliográficos
Autores principales: Hou, Shenda, Clement, Rachel L., Diallo, Alos, Blazar, Bruce R., Rudensky, Alexander Y., Sharpe, Arlene H., Sage, Peter T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2019
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6400538/
https://www.ncbi.nlm.nih.gov/pubmed/30705058
http://dx.doi.org/10.1084/jem.20181134

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6400538/
https://www.ncbi.nlm.nih.gov/pubmed/30705058
http://dx.doi.org/10.1084/jem.20181134

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