Cargando…

A major role for ferroptosis in Mycobacterium tuberculosis–induced cell death and tissue necrosis

Necrotic cell death during Mycobacterium tuberculosis (Mtb) infection is considered host detrimental since it facilitates mycobacterial spread. Ferroptosis is a type of regulated necrosis induced by accumulation of free iron and toxic lipid peroxides. We observed that Mtb-induced macrophage necrosis...

Descripción completa

Detalles Bibliográficos
Autores principales: Amaral, Eduardo P., Costa, Diego L., Namasivayam, Sivaranjani, Riteau, Nicolas, Kamenyeva, Olena, Mittereder, Lara, Mayer-Barber, Katrin D., Andrade, Bruno B., Sher, Alan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6400546/
https://www.ncbi.nlm.nih.gov/pubmed/30787033
http://dx.doi.org/10.1084/jem.20181776