Cargando…
A major role for ferroptosis in Mycobacterium tuberculosis–induced cell death and tissue necrosis
Necrotic cell death during Mycobacterium tuberculosis (Mtb) infection is considered host detrimental since it facilitates mycobacterial spread. Ferroptosis is a type of regulated necrosis induced by accumulation of free iron and toxic lipid peroxides. We observed that Mtb-induced macrophage necrosis...
Autores principales: | Amaral, Eduardo P., Costa, Diego L., Namasivayam, Sivaranjani, Riteau, Nicolas, Kamenyeva, Olena, Mittereder, Lara, Mayer-Barber, Katrin D., Andrade, Bruno B., Sher, Alan |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6400546/ https://www.ncbi.nlm.nih.gov/pubmed/30787033 http://dx.doi.org/10.1084/jem.20181776 |
Ejemplares similares
-
Enhancement of CD4(+) T Cell Function as a Strategy for Improving Antibiotic Therapy Efficacy in Tuberculosis: Does It Work?
por: Costa, Diego L., et al.
Publicado: (2021) -
Correlation between Disease Severity and the Intestinal Microbiome in Mycobacterium tuberculosis-Infected Rhesus Macaques
por: Namasivayam, Sivaranjani, et al.
Publicado: (2019) -
Heme oxygenase-1 inhibition promotes IFNγ and NOS2 mediated control of Mycobacterium tuberculosis infection
por: Costa, Diego L, et al.
Publicado: (2020) -
GPX4 regulates cellular necrosis and host resistance in Mycobacterium tuberculosis infection
por: Amaral, Eduardo P., et al.
Publicado: (2022) -
Pharmacological Inhibition of Host Heme Oxygenase-1 Suppresses Mycobacterium tuberculosis Infection In Vivo by a Mechanism Dependent on T Lymphocytes
por: Costa, Diego L., et al.
Publicado: (2016)