Cul4 ubiquitin ligase cofactor DCAF12 promotes neurotransmitter release and homeostatic plasticity

We genetically characterized the synaptic role of the Drosophila homologue of human DCAF12, a putative cofactor of Cullin4 (Cul4) ubiquitin ligase complexes. Deletion of Drosophila DCAF12 impairs larval locomotion and arrests development. At larval neuromuscular junctions (NMJs), DCAF12 is expressed...

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Detalles Bibliográficos
Autores principales: Patrón, Lilian A., Nagatomo, Kei, Eves, David Tyler, Imad, Mays, Young, Kimberly, Torvund, Meaghan, Guo, Xiufang, Rogers, Gregory C., Zinsmaier, Konrad E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2019
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6400570/
https://www.ncbi.nlm.nih.gov/pubmed/30670470
http://dx.doi.org/10.1083/jcb.201805099

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6400570/
https://www.ncbi.nlm.nih.gov/pubmed/30670470
http://dx.doi.org/10.1083/jcb.201805099

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