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An atlas of polygenic risk score associations to highlight putative causal relationships across the human phenome
The age of large-scale genome-wide association studies (GWAS) has provided us with an unprecedented opportunity to evaluate the genetic liability of complex disease using polygenic risk scores (PRS). In this study, we have analysed 162 PRS (p<5×10(−05)) derived from GWAS and 551 heritable traits...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
eLife Sciences Publications, Ltd
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6400585/ https://www.ncbi.nlm.nih.gov/pubmed/30835202 http://dx.doi.org/10.7554/eLife.43657 |