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Lyn Kinase Promotes the Proliferation of Malignant Melanoma Cells through Inhibition of Apoptosis and Autophagy via the PI3K/Akt Signaling Pathway

Melanoma is a malignant tumor of cutaneous melanocytes that is characterized by high grade malignancy, rapid progression and high mortality. Thus far, its specific etiological mechanism has been unclear. In this study, we discovered that Lyn kinase expression was up-regulated in melanoma tissues and...

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Detalles Bibliográficos
Autores principales: Zhang, Qianqian, Meng, Xianguang, Qin, Guojing, Xue, Xiaotong, Dang, Ningning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6400685/
https://www.ncbi.nlm.nih.gov/pubmed/30854129
http://dx.doi.org/10.7150/jca.28908