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Downregulation of PDK4 Increases Lipogenesis and Associates with Poor Prognosis in Hepatocellular Carcinoma

Alterations in cellular metabolism are one of the characteristics in cancer. They are not only the result of tumor progression but also the cause of cancer initiation. Pyruvate dehydrogenase kinase 4 (PDK4) is a key metabolic enzyme, which regulates cell metabolism by inhibiting pyruvate dehydrogena...

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Detalles Bibliográficos
Autores principales: Yang, Chen, Wang, Siying, Ruan, Haoyu, Li, Botai, Cheng, Zhuoan, He, Jia, Zuo, Qiaozhu, Yu, Chengtao, Wang, Hui, Lv, Yuanyuan, Gu, Dishui, Jin, Guangzhi, Yao, Ming, Qin, Wenxin, Jin, Haojie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6400816/
https://www.ncbi.nlm.nih.gov/pubmed/30854098
http://dx.doi.org/10.7150/jca.27226