Characterization of Brain Lysosomal Activities in GBA-Related and Sporadic Parkinson’s Disease and Dementia with Lewy Bodies

Mutations in the GBA gene, encoding the lysosomal hydrolase glucocerebrosidase (GCase), are the most common known genetic risk factor for Parkinson’s disease (PD) and dementia with Lewy bodies (DLB). The present study aims to gain more insight into changes in lysosomal activity in different brain re...

Descripción completa

Detalles Bibliográficos
Autores principales: Moors, Tim E., Paciotti, Silvia, Ingrassia, Angela, Quadri, Marialuisa, Breedveld, Guido, Tasegian, Anna, Chiasserini, Davide, Eusebi, Paolo, Duran-Pacheco, Gonzalo, Kremer, Thomas, Calabresi, Paolo, Bonifati, Vincenzo, Parnetti, Lucilla, Beccari, Tommaso, van de Berg, Wilma D. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6400877/
https://www.ncbi.nlm.nih.gov/pubmed/29948939
http://dx.doi.org/10.1007/s12035-018-1090-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6400877/
https://www.ncbi.nlm.nih.gov/pubmed/29948939
http://dx.doi.org/10.1007/s12035-018-1090-0

Ejemplares similares