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Screening for HPV infection in exfoliated cervical cells of women from different ethnic groups in Yili, Xinjiang, China

We investigated the infection status and genotype distribution of human papillomavirus (HPV) in women of different ages and various ethnic groups in the Yili region, Xinjiang, China. We checked the HPV genotypes of 3,445 samples of exfoliated cervical cells using the PCR–reverse dot blot method. The...

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Autores principales: Pan, Zhenzhen, Song, Yuning, Zhe, Xiangyi, Wang, Weibin, Zhu, Junling, Zheng, Weinan, Li, Hongtao, Li, Dongmei, Cao, Dongdong, Pan, Zemin, Shao, Renfu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6400895/
https://www.ncbi.nlm.nih.gov/pubmed/30837516
http://dx.doi.org/10.1038/s41598-019-39790-2
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author Pan, Zhenzhen
Song, Yuning
Zhe, Xiangyi
Wang, Weibin
Zhu, Junling
Zheng, Weinan
Li, Hongtao
Li, Dongmei
Cao, Dongdong
Pan, Zemin
Shao, Renfu
author_facet Pan, Zhenzhen
Song, Yuning
Zhe, Xiangyi
Wang, Weibin
Zhu, Junling
Zheng, Weinan
Li, Hongtao
Li, Dongmei
Cao, Dongdong
Pan, Zemin
Shao, Renfu
author_sort Pan, Zhenzhen
collection PubMed
description We investigated the infection status and genotype distribution of human papillomavirus (HPV) in women of different ages and various ethnic groups in the Yili region, Xinjiang, China. We checked the HPV genotypes of 3,445 samples of exfoliated cervical cells using the PCR–reverse dot blot method. The total infection rate of HPV was 25.60% (882/3,445). The ethnic stratification showed that the infection rates were 22.87% (196/857) in Uygur, 21.55% (122/566) in Kazak, and 27.89% (564/2,022) in Han individuals. The most prevalent high-risk genotypes were HPV16, HPV52, and HPV53 in Uygur and Kazak and HPV16, HPV52, and HPV58 in Han ethnic groups. The age stratification showed that the infection rates in Han, Uygur, and Kazak women were up to 40.9% (61/149) in those aged 26–30 years, 41.5% (22/53) in those over 61 years old, and 30.2% (29/96) in those 46–50 years old, respectively. Therefore, HPV infection and HPV genotype distribution varied among the different age groups of the three ethnic groups.
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spelling pubmed-64008952019-03-07 Screening for HPV infection in exfoliated cervical cells of women from different ethnic groups in Yili, Xinjiang, China Pan, Zhenzhen Song, Yuning Zhe, Xiangyi Wang, Weibin Zhu, Junling Zheng, Weinan Li, Hongtao Li, Dongmei Cao, Dongdong Pan, Zemin Shao, Renfu Sci Rep Article We investigated the infection status and genotype distribution of human papillomavirus (HPV) in women of different ages and various ethnic groups in the Yili region, Xinjiang, China. We checked the HPV genotypes of 3,445 samples of exfoliated cervical cells using the PCR–reverse dot blot method. The total infection rate of HPV was 25.60% (882/3,445). The ethnic stratification showed that the infection rates were 22.87% (196/857) in Uygur, 21.55% (122/566) in Kazak, and 27.89% (564/2,022) in Han individuals. The most prevalent high-risk genotypes were HPV16, HPV52, and HPV53 in Uygur and Kazak and HPV16, HPV52, and HPV58 in Han ethnic groups. The age stratification showed that the infection rates in Han, Uygur, and Kazak women were up to 40.9% (61/149) in those aged 26–30 years, 41.5% (22/53) in those over 61 years old, and 30.2% (29/96) in those 46–50 years old, respectively. Therefore, HPV infection and HPV genotype distribution varied among the different age groups of the three ethnic groups. Nature Publishing Group UK 2019-03-05 /pmc/articles/PMC6400895/ /pubmed/30837516 http://dx.doi.org/10.1038/s41598-019-39790-2 Text en © The Author(s) 2019 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Article
Pan, Zhenzhen
Song, Yuning
Zhe, Xiangyi
Wang, Weibin
Zhu, Junling
Zheng, Weinan
Li, Hongtao
Li, Dongmei
Cao, Dongdong
Pan, Zemin
Shao, Renfu
Screening for HPV infection in exfoliated cervical cells of women from different ethnic groups in Yili, Xinjiang, China
title Screening for HPV infection in exfoliated cervical cells of women from different ethnic groups in Yili, Xinjiang, China
title_full Screening for HPV infection in exfoliated cervical cells of women from different ethnic groups in Yili, Xinjiang, China
title_fullStr Screening for HPV infection in exfoliated cervical cells of women from different ethnic groups in Yili, Xinjiang, China
title_full_unstemmed Screening for HPV infection in exfoliated cervical cells of women from different ethnic groups in Yili, Xinjiang, China
title_short Screening for HPV infection in exfoliated cervical cells of women from different ethnic groups in Yili, Xinjiang, China
title_sort screening for hpv infection in exfoliated cervical cells of women from different ethnic groups in yili, xinjiang, china
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6400895/
https://www.ncbi.nlm.nih.gov/pubmed/30837516
http://dx.doi.org/10.1038/s41598-019-39790-2
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