Regional perturbation of gene transcription is associated with intrachromosomal rearrangements and gene fusion transcripts in high grade ovarian cancer

Genomic rearrangements are a hallmark of cancer biology and progression, allowing cells to rapidly transform through alterations in regulatory structures, changes in expression patterns, reprogramming of signaling pathways, and creation of novel transcripts via gene fusion events. Though functional...

Descripción completa

Detalles Bibliográficos
Autores principales: Krzyzanowski, Paul M., Sircoulomb, Fabrice, Yousif, Fouad, Normand, Josee, La Rose, Jose, E. Francis, Kyle, Suarez, Fernando, Beck, Tim, McPherson, John D., Stein, Lincoln D., Rottapel, Robert K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6401071/
https://www.ncbi.nlm.nih.gov/pubmed/30837567
http://dx.doi.org/10.1038/s41598-019-39878-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6401071/
https://www.ncbi.nlm.nih.gov/pubmed/30837567
http://dx.doi.org/10.1038/s41598-019-39878-9

Ejemplares similares