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Striatal Interneurons in Transgenic Nonhuman Primate Model of Huntington’s Disease

Huntington’s disease is an autosomal dominant neurodegenerative disorder associated with progressive motor and cognitive impairments, and the expansion of a cysteine-adenine-guanine trinucleotide (polyglutamine) repeats in exon one of the human huntingtin gene. The pathology of the disease is charac...

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Detalles Bibliográficos
Autores principales: Lallani, Shoeb B., Villalba, Rosa M., Chen, Yiju, Smith, Yoland, Chan, Anthony W. S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6401084/
https://www.ncbi.nlm.nih.gov/pubmed/30837611
http://dx.doi.org/10.1038/s41598-019-40165-w