The landscape of d16HER2 splice variant expression across HER2-positive cancers

The HER2 splice variant characterized by the deletion of exon 16 and denominated as d16HER2, is associated with HER2-positive breast cancer (BC) aggressiveness, stemness, and trastuzumab susceptibility and is considered to be a “flag” of HER2 dependence. However, with the exception of quantitative r...

Descripción completa

Detalles Bibliográficos
Autores principales: Volpi, Chiara Costanza, Pietrantonio, Filippo, Gloghini, Annunziata, Fucà, Giovanni, Giordano, Silvia, Corso, Simona, Pruneri, Giancarlo, Antista, Maria, Cremolini, Chiara, Fasano, Elena, Saggio, Serena, Faraci, Simona, Di Bartolomeo, Maria, de Braud, Filippo, Di Nicola, Massimo, Tagliabue, Elda, Pupa, Serenella Maria, Castagnoli, Lorenzo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6401102/
https://www.ncbi.nlm.nih.gov/pubmed/30837627
http://dx.doi.org/10.1038/s41598-019-40310-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6401102/
https://www.ncbi.nlm.nih.gov/pubmed/30837627
http://dx.doi.org/10.1038/s41598-019-40310-5

Ejemplares similares