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Vegfa/vegfr2 signaling is necessary for zebrafish islet vessel development, but is dispensable for beta-cell and alpha-cell formation
The mechanisms underlying zebrafish pancreatic islet vascularization have not been well characterized. We sought to determine the angiogenic factors responsible for islet vascularization and assess whether an absence of endothelial cells affects beta-cell and alpha-cell formation. We used a double t...
Autores principales: | Toselli, Chiara M., Wilkinson, Brayden M., Paterson, Joshua, Kieffer, Timothy J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6401103/ https://www.ncbi.nlm.nih.gov/pubmed/30837605 http://dx.doi.org/10.1038/s41598-019-40136-1 |
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