A permeability-increasing drug synergizes with bacterial efflux pump inhibitors and restores susceptibility to antibiotics in multi-drug resistant Pseudomonas aeruginosa strains

Resistance to antibiotics poses a major global threat according to the World Health Organization. Restoring the activity of existing drugs is an attractive alternative to address this challenge. One of the most efficient mechanisms of bacterial resistance involves the expression of efflux pump syste...

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Detalles Bibliográficos
Autores principales: Ferrer-Espada, Raquel, Shahrour, Hawraa, Pitts, Betsey, Stewart, Philip S., Sánchez-Gómez, Susana, Martínez-de-Tejada, Guillermo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6401119/
https://www.ncbi.nlm.nih.gov/pubmed/30837499
http://dx.doi.org/10.1038/s41598-019-39659-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6401119/
https://www.ncbi.nlm.nih.gov/pubmed/30837499
http://dx.doi.org/10.1038/s41598-019-39659-4

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